In this paper, we propose a Flexible processing-in-DRAM framework named FlexiDRAM that supports the efficient implementation of complex bulk bitwise operations. This framework is developed on top of a new reconfigurable in-DRAM accelerator that leverages the analog operation of DRAM sub-arrays and elevates it to implement XOR2-MAJ3 operations between operands stored in the same bit-line. FlexiDRAM first generates an efficient XOR-MAJ representation of the desired logic and then appropriately allocates DRAM rows to the operands to execute any in-DRAM computation. We develop ISA and software support required to compute in-DRAM operation. FlexiDRAM transforms current memory architecture to a massively parallel computational unit and can be leveraged to significantly reduce the latency and energy consumption of complex workloads. Our extensive circuit-to-architecture simulation results show that averaged across two well-known deep learning workloads, FlexiDRAM achieves ∼ 15 × energy-saving and 13 × speedup over the GPU outperforming recent processing-in-DRAM platforms.